When I did my routine check, she was “down” in her hindquarters. I called a ruminant veterinarian at ISU and he suggested 5mg/ # IM or if the animal is extremely ill 5mg/# IM and IV simultaneously. Amprolium effectively competes with thiamine for uptake into the brain which therefore can induce PEM. Thiamine, also known as vitamin B1, is normally produced by bacteria in the rumen of cattle and sheep on well-balanced roughage diets. I give her a Vitamin B-Complex shot and forget the penicillin; probiotics ok; I am curious as to what the outcome was for your goat if you donât mind me asking. production. As with many disorders and disease conditions, early detection is key for successful treatment. Thiamine is not produced in animal cells but is produced by rumen microbes, which provide the major source of thiamine to adult sheep and goats. Effective but slightly more risky therapy would be to inject the first dose slowly intravenously (IV) followed by another dose provided intramuscularly (IM). In summer we are also under a lot more stress with showing and weaning. An increase in Goat Polio occurs in North America during winter, when the availability of forage and quality hay is low and … PEM is a pathologic diagnosis and a common end point of several conditions. Goats need little minding. Also in Tetanus the joints cannot be manually bent while in Polio they are flexible. 3. Goats. She was treated for tetanus, bacterial infection and Polio. illness defined by a collection of symptoms that generally occur at least 10-20 years after infection with the polio virus This disorder may be acute or sub-acute in nature. She was treated immediately, she was stronger in 10-15 minutes and fully recovered in about thirty minutes, but we did continue to watch her for 24 hours. She was also blind but within the next few weeks she recovered fully including her sight. The gift of a she-goat can result in self-sufficiency for a polio survivor. Last summer my son was walking through the barn and noticed a doeling standing in a corner with tremors and staggering when she walked. Goats are particularly reliant on one of the thiamine-dependent methods of glucose metabolism. Goat Polio is generally seen most often in weanlings and young adults , in contrast to Listeriosis, which most frequently affects adult goats. The sulfur content of these feeds may vary according to the processing plant or even the batch, as much of the additional sulfur content in these by products results from addition of acidifying agents such as sulfuric acid during the production process. Hi Jen – this is Guinevere McIntyre. The usage of these sulfur-rich products varies across ethanol plants, so blanket statements regarding ethanol by-product feeds as being high in sulfur cannot be made. A few years later a goat “went down” at a very hot county fair. Polioencephalomalacia (PEM) is also known as cerebrocortical necrosis (CCN) and is a relatively common nutritional disorder in sheep and goats. If unsure, it is Cases of PEM can be successfully treated if detected early in the disease course, making recognition of early symptoms a critical issue for sheep and goat producers. Therefore, it is difficult to develop an effective prevention program for these cases, although making gradual dietary transitions will certainly reduce the incidence of PEM along with many other health concerns. Repeat injection daily for 2-3 days if necessary. Mine is currently under the same treatment right now. Signs of polio vary. If unsure, TREAT. Induction of PEM with amprolium in uncommon but not rare. Today, despite a worldwide effort to wipe out polio, poliovirus continues to affect children and adults in parts of Asia and Africa.The Centers for Disease Control and Prevention (CDC) advises taking precautions to protect yourself from polio i… Either way the result is Thiamine deficiency. In the winter my goats are on maintenance only. Polio is a life-threatening disease caused by a virus. Goat polio is usually seen in animals that are I usually use 1-2cc of 200mg/ml on a small kid and 6-8 cc on an adult animal, IM. God Bless. What exactly are his symptoms, is he just lethargic or is it more than that? Metabolic means relating to metabolism, the whole range of biochemical processes that occur within the goat's rumen. 4. The grain releases carbohydrate into the animal's rumen and this rapidly ferments rather than being digested normally. Early blindness symptoms lead within hours to a day to loss of body control, inability to stand, and seizures. My first experience with Polio was about ten years ago. Experts are still unsure what's causing the … Length of recovery will depend on how long the animal has been sick. Thiamine is especially important for proper brain function as the brain relies on glucose as its major source of energy. Most PEM cases are isolated and sporadic in nature; however, a higher incidence may occur in lamb/kids on finishing diets. We got her out of pen and started treating with 6cc of 2000mg/ml thiamine and 6cc of dexamethasone iv, and then every 6 hours: 6cc of thiamine and 10cc of procaine penicillin. Entertoxemia is a frequently severe disease of sheep and goats of all ages. The most common cause of PEM is thiamine deficiency. It is common for the pupils to be dilated and for the eyes to tear. Other causes may include but are not limited to prolonged treatment with higher than recommended doses of Corid (amprolium), deworming, grazing on recently fertilized pasture, high sulfur intake (as from water), and rarely published but one of the most common causes I have seen, STRESS. Use 1.5ml/25# body weight or 6ml per 100# body weight of 300,000 Iu/ml. Many of those have been treated successfully, so I hope this will be helpful to you. Cattle, sheep, goats, deer, and camelids are affected. A major cause is feeding a diet rich in concentrate ration and low in roughage. 1. Rumen acidosis, or an abnormal acidic environment within the first stomach of ruminants, develops with the rapid fermentation of highly digestible carbohydrates that are ingested in excessive amounts. It is sometimes advantageous to treat with Procaine Penicillin to cover Listeriosis, in doses high enough to cross the blood-brain barrier. I don’t believe he can use it orally, it has to be given as a shot for his body to process it. Remember Thiamine is water soluble; you can’t harm a goat by misdiagnosis or over treatment. Vitamin B complex formulations can be purchased containing thiamine, but it is highly recommended that producers have a bottle of concentrated thiamine on hand (250 to 500 mg/mL) at all times. In the early 1950s, before polio vaccines were available, polio outbreaks caused more than 15,000 cases of paralysis each year. Your email address will not be published. Polioencephalomalacia (PEM) is also known as cerebrocortical necrosis (CCN) and is a relatively common nutritional disorder in sheep and goats. You won’t overdose. Polioencephalomalacia (PEM), commonly referred to in livestock as polio, is a common metabolic disorder characterized by neuromuscular alterations of goats and sheep that are thiamine deficient. Please help with any advise you have. It turns out that a really high-carb diet might be especially bad for your goats.